Saturday, September 7, 2019

Sapporo beer Essay Example for Free

Sapporo beer Essay Japan’s Sapporo Holdings said on Thursday it would enter the Vietnamese market by taking a 65 percent stake in a beer joint venture with Vietnam National Tobacco Corp to tap its fast-growing market. It marks the first major overseas expansion in three years by Sapporo, the smallest of Japan’s four major brewers, as bigger rivals Kirin and Suntory have been aggressively snapping up overseas businesses to grow beyond a shrinking domestic market. â€Å"Vietnam is Asia’s third-largest beer market after China and Japan and this is a fast-growing market,† said Tatsuya Komatsu, a Sapporo spokesman. The company will acquire a 50 percent stake in the venture from Danish brewer Carlsberg and 15 percent from Vietnam National Tobacco for a total of $25. 4 million. The joint venture will build a beer factory in Vietnam and is scheduled to startselling Sapporo brand beer in early 2012, it said in a statement. The venture aims for sales in 2019 of 150,000 kilolitres or $128 million. Sapporo said it will actively seek further acquisition opportunities to enlarge itsoverseas business, which now accounts for less than 10 percent of its revenues. Sapporo, the maker of Yebisu brand beer, acquired Canadian brewer Sleeman in 2006 for 30 billion yen ($340 million), but has been overshadowed by Kirin and Suntory in overseas expansion. Kirin has spent $1. 5 billion in the past two years to buy Australia’s National Foods and Dairy Farmers and $2. 8 billion to take full ownership of Australia’s No. 2 beer maker Lion Nathan. It also acquired a 49 percent stake in the Philippines’ San Miguel Brewery for $1. 4 billion. Asahi Breweries, locked in a fierce battle with Kirin for No. 1 slot in Japan’s beer market, said recently it could spend up to 400 billion yen ($4. 6 billion) on acquisitions over the next few years, with an eye on Asian markets. The Japanese brewers have been scrambling to diversify their products and geographic reach to reduce their reliance on the domestic beer market, which has lost 15 percent in volume in the past decade as the economy sputters and the population shrinks. HA NOI — The Japanese beer maker Sapporo Holdings plans to enter the domestic market from early 2012 through the purchase of a majority stake in Kronenbourg Viet Nam Ltd. Sapporo Holdings said it would buy a 65 per cent stake for about US$23 million in Kronenbourg Viet Nam, which is equally owned by Carlsberg Brewery A/S and the Viet Nam National Tobacco Corp (Vinataba). After the deal closes, which is due in January next year, a joint venture betweenSapporo Holdings and Vinataba will be set up with the latter holding 35 per cent of the joint venture’s stake. At that time, Kronenbourg Viet Nam will change its name into Sapporo Viet Nam Ltd. Sapporo said the joint venture would begin construction on a new plant on the outskirts of HCM City. The plant is scheduled to begin operations from 2012. Sapporo expects to earn a turnover of roughly $115 million within a decade from the Vietnamese market, with a predicted annual growth rate of more than 10 per cent for years to come. The joint venture has targeted a market share of roughly 3 per cent in Viet Nam by 2019. Sapporo also has plans to export beer produced in Japan to Viet Nam. The Japanese beer maker decided to expand its business in other Asian countries in a move to offset declining beer sales in Japan due to a shrinking population and a gloomy economic outlook. — VNS In 2010 , Sapporo has arrived in Vietnam and established Sapporo Vietnam Co. ( a joint venture between Tobacco Corporation Vietnam ( VINATABA ) and JSC Sapporo Holdings Ltd. for a total contribution from Japan 71 % ) . 11/ 2011, the Sapporo Factory in Long An Vietnam was officially put into operation . The plant has production capacity of 40 million liters / year , but to meet the goal of becoming a major production base for Southeast Asian beer market capacity will be increased gradually over the period 2015 to reach 100 million liters / year and in 2019 will reach 150 million liters / year . 4/2012 , Sapporo official launch sales activities . Sapporo time in more than 4,000 retail stores , restaurants , hotels, mainly in Vietnam . Sapporo has now launched 4 product lines premium beer : Sapporo Premium Beer Bottle 330 ml , 330 ml cans of beer Sapporo Premium , Sapporo Premium Beer 650 ml silver cans and beer Sapporo Premium 20L . In particular , products Can Silver ( silver cans ) is a typical representative of elegance and luxury of Sapporo Premium Beer . This product has a higher alcohol content than other types a bit , with a large capacity and a unique design that Sapporo beer can only be Sapporo is the only beer company in the world combined study of barley and hops to produce a formula to create the most perfect beer . Based on these studies , the Sapporo today have developed a new barley varieties better and Vietnam Sapporo Factory is also used . When the Vietnam market , to be able to produce beers with similar quality beers produced in Japan and in accordance with consumer tastes here , Sapporo choose the most appropriate type of yeast in 1000 different yeast species from the research Center of Sapporo in Japan . After Japan and Canada , Vietnam is the place where Sapporo beer factory and expect this will become the manufacturing center of the Southeast Asian market . Because Vietnam is the third largest beer market in Asia , the turnover of 3 billion liters of beer in 2020 and expected to double . Sapporo Vietnam not only passionate creative challenges overcome and the framework of the usual practice , but also to share the moments of happiness and joy winning hand. Thats why Sapporo Premium market presence in Vietnam as a premium beer brand .

Friday, September 6, 2019

Establish and adjust the markrting mix Essay Example for Free

Establish and adjust the markrting mix Essay 1. Research Your Choice of organization Kentucky Fried Chicken (KFC)- one of the most known fast food chains in the world started in the early 1930s by Kernel Sanders in the Southern USA as a small franchise operation. Colonel Sanders has become a well-known personality throughout thousands of KFC restaurants Worldwide. Quality, service and cleanliness (QSC) represents the most critical success factors to KFCs global success. KFC has a number of ambitious aims and objectives: To increase its percentage share of the fast-food market. To improve profit margins year-on-year to fund the growth of the company. To return profit on investments to owners and franchisees. The way that KFC reaches these targets is decided by the companys internal strategy and objectives. Company and Marketing Strategy: Partnering to build customer relationships a. Marketing Strategy KFC used the Demographic Segmentation, Geographic segmentation, and Psychographic segmentation. In demographic segmentation, the market is divided into groups based on an age, gender, family size, income, occupation, religion, race and nationality. KFC divides the market on demographic basis in this way: ïÆ'Ëœ Age is between 6-65. Gender is both males and females. Family size is 1-2, 3-4, 5+ Income is Rs 10,000 n above. Family lifestyle is almost all. KFC has outlets internationally and sells its products according to geographic needs of the customer. In India KFC focuses how geographically its customers demand different products. In north India Chicken is the main selling product, while in the south the Veg. items sell more than the chicken. Dividing a market into different groups based on social class, lifestyle, or personality characteristics is called psychographic segmentation. KFC divides market on the basis of psychographic variables like: Social class- Upper and Middle class. Lifestyle is not specific. Personality is ambitious and authoritarian b. Target Marketing As the outlets of KFC are in posh area and prices are too high (overhead expenses-rent, air-conditioning, employees), so KFC targets upper and middle classes. Target market depends upon size and growth rate of population, Company resources and structural attractiveness of market segment. c. Market Positioning For a product to occupy a clear, distinctive and desirable place relative to â€Å"Competing products in the minds of target consumer.† In KFC feedback is taken from the customer in order to know the customer demands and then improvements are made in products. KFC focuses on pure and fresh food in order to create a distinct and clear position in the minds of customers KFC has a strong brand name and they are leading the market in fried chicken. 2. Identify the Key Characteristics of their products and services and their significance to the market. Product Line: KFC product line includes all chicken based products. Burgers: The burger category includes the Zinger Burger, Colonel’s Chicken Burger, Colonel’s Fillet Burger, SUB60 and 80, and Zinger Jr. They have also introduces a Fish zinger burger. Chicken Pieces: The chicken involved the product line with different number of chicken pieces like 1 piece, 2 pieces, 5 pieces and 10 pieces chicken. Combos: The combo includes the different meal as Chicken Meals, Sandwich Meals and Family Meals. Desserts Beverages: The desserts and beverages offered by KFC are Fruit Salad, Regular Large Drink, Regular Large Mineral Water, Tea, Scoop of Walls Ice cream and Coffee. Snacks Side Orders: The snacks and side orders served by the KFC are Arabian Rice, 5 10 Pieces Hot wings, Dinner Roll, Regular Large Fries, Hot Shots, and Corn on the  Cob, Hot Crispy Soup and the Cole Slaw. 3. Review pricing policy and analyse pricing variables to determine their effect on demand.

Thursday, September 5, 2019

Vulnerable Subjects Research

Vulnerable Subjects Research PROTECTION OF VULNERABLE SUBJECTS IN CLINICAL TRIALS BACKGROUND Aim: To throw light on the state of vulnerable subjects in Clinical Research. Objective: To understand current provisions and legislations available to protect the rights of vulnerable subjects with special emphasis on plight of sex workers enrolled in anti-HIV trials. VULNERABLE SUBJECTS IN CLINICAL RESEARCH Individuals who are comparatively or entirely inept of defending their own wellbeing are termed as vulnerable research participants. When study includes such subjects additional care has to be taken to protect their rights. It is the investigator and his research team’s responsibility to ensure that these subjects are not exploited in the name of research. The study design team, sponsor, investigator must be aware of the special requirements needed for vulnerable subjects and they should develop the study protocol, informed consent form and the confidentiality agreement keeping the vulnerable subjects’ needs in mind. The different types of vulnerable subjects included in clinical trials are classified on basis of their vulnerability. Some examples are as follows: 1. Cognitive and Communicative vulnerability: This includes children and adolescents. Patient’s suffering from mental retardation, dementia and other kinds of mental illness. Enrollment of people with educational deficits and unfamiliarity with language. Stressful emergency: conditions that do not permit otherwise capable adults to implement their capabilities efficiently. 2. Juridical or institutional vulnerability: Person who is under the official authority of others (egs. Parents, guardians, warders, officers and judges) who may have their own benefits in whether the individual agrees to enroll in the study. 3. Deferential vulnerability: Influence of other people in subjects life, determine their decision to enter the trial. Existence of an informal hierarchy (egs. Relatives, friends, masters, physician) 4. Medical vulnerability: Prospective patients who have a severe medical condition, for which there are no existing efficient or satisfactory regular cure (examples: very aggressive and malignant forms of cancer, last stage AIDS and some uncommon ailments) owing to their unusual medically tricky state, misuse of these patients throughout their hope for remission or improvement is not unusual. 5. Economic vulnerability: Prospective subjects with low economic background may join trial with hope of getting income, housing and healthcare facilities. Payment for participation or free access to healthcare services might constitute unfair inducements to enroll through exploitation of these subjects. 6. Infrastructural vulnerability: Patient is tempted to enroll in trials, as they pre-suppose the availability to them of resources or facilities (egs. a rapid communication system, a reliable dietary intake, skilled healthcare professionals) 7. Social vulnerability: Refers to individuals belonging to undervalued social groups or communities.(sex workers)[R. Colombo, The Most Vulnerable Subjects Of Biomedical Research IX General Assembly PAV – publications] EXPLOITATION OF VULNERABLE SUBJECTS THROUGH HISTORY Exploitation was rampant in the absence of regulations, laws, guidelines and codes. Escalating physician to god-like position with immense faith in them and failure to recognize vulnerable subjects has resulted in horrific incidents in history of research. These major mishaps have convinced the medical fraternity the need for developing ethical guidelines and code for research specifically for the vulnerable populations. The Nuremberg trial The 20th century will always be remembered due to the shocking and upsetting experimentation performed by Nazi doctors. During the World War II, the Nazi physicians took advantage of the prisoners of war; they carried out experiments unparalleled in their range and the level of anguish and harm. Appalling studies such as injecting the poor prisoners with gasoline and live viruses, immersing people in ice water, and forcing them to ingest poisons have gone down in the history books as the most inhuman experiments. The physicians in order to satisfy their scientific curiosity have performed these experiments which were of no use to the participants. These experiments usually resulted in the death of the participants. After the war ended, there was a huge public outburst against these experiments and 23 physicians were indicted at Nuremberg for their willing participation in these experiments. Sixteen were found guilty and sentenced while seven were hanged to death. This resulted in the origin of the Nuremberg Code, which made informed consent mandatory. The Willowbrook study The Nuremberg Code unfortunately did not put to end unethical research as not every researcher honored the Code. The three year long Willowbrook study is another example where vulnerable patients were exploited. Willowbrook State School, an institution for mentally defective children were intentionally infect with the hepatitis virus, by being fed stools from infected persons or later by being injecting with purified virus preparations, to observe the natural history of this disease and then to test the effects o gamma globulin in preventing the disease. Researchers defended the deliberate infection of these children by stating that the bulk of them acquired the infection in any case while at Willowbrook, and possibly it would be better for them to be infected under restricted research settings. What was worse was that during the course of these studies, new inmates were admitted only if they agreed to participate in the hepatitis program! There was obviously no full disclosure ad clearly coercion and undue pressure was used to enroll vulnerable subjects like children and mentally challenged. Jewish Chronic Disease Hospital Study At the other end of life’s spectrum, came the Jewish Chronic Disease Hospital Study where live cancer cells were infused into continually ailing and incapacitated patients. These patients had been told that they were getting a skin examination. The patients were provided oral information about the test but no consent was documented. Syphilis study The most notorious example of prolonged infringement of human rights of a vulnerable faction of research participants was the long-term study of black males performed at Tuskegee by the United States Public Health Service. Initiated in the 1930s to examine the natural history of untreated syphilis, continuing until 1972, this study recruited more than 400 black men suffering from syphilis. These participants were recruited without informed consent and were mislead that a few of the measures taken in the interest of research were essentially â€Å"special complimentary treatment†. Although along the way antibiotics become available, these were not given to the patients and the study resulted in 28 deaths, 100 cases of disability, and 19 cases of congenital syphilis. The Belmont report published by the National Commission for the Protection of Human Subjects of Biomedical and Behavioral Research on April 18, 1979 was one of the outcomes of the public outcry that resulted when the story of the Tuskegee study broke.[Urmila Thatte, Etical issues in clinical Research chapter 4, of Basic principles of clinical research and methodology by S K Gupta] Guidelines for ethical conduct of research in human subjects that have came into picture: Nuremberg Code, 1947 Declaration of Helsinki, 1964 The Belmont Report, 1979 International Ethical Guidelines for Biomedical Research Involving Human Subjects, 1982, 1993, 2002 The Ethics of Research related to Healthcare in Developing Countries, Nuffield council, 2002 Indian council for Medical Research Ethical Guidelines for Biomedical Research on Human subjects SPECIAL CONSIDERATIONS FOR CHILDREN Regulations that protect children, so as to prevent their exploitation are: OHRP 45 CFR 46 Subpart D FDA 21 CFR 50 Subpart D Special Considerations for Children are: Research that involves no more than minimal risk can be approved with adequate provisions for obtaining the assent of the child and permission from their parents/guardians. 45 CFR 46.404 The combination of assent by the minor subject and permission (consent) from the parents is deemed appropriate to enroll the child subject in the trial. In case of life threatening events only consent from parents would suffice, as there is expectation of direct benefit. However the child must be given full explanation of the trial. If the research presents an opening to comprehend, avoid or lessen a grave predicament affecting the health or welfare of children, but does NOT provide direct benefit to the subject or societal (indirect) benefit, than the research cannot be approved by the IRB unless HHS Secretary Approval is granted. 45 CFR 46.407 . Extremely rare- both Parent consent + child assent. When parents of the child are deceased, unknown or incompetent then the legal guardian must give is consent. Step parents, Grandparents, Adult siblings, adult Aunts or Uncles may not consent a child to research. SPECIAL CONSIDERATIONS FOR WOMEN Regulations that protect women, so as to prevent their exploitation are: OHRP 45 CFR 46 Subpart B Research studies involving pregnant women and fetuses must satisfy the following requirements to obtain IRB approval: Preclinical studies have been conducted, including studies on pregnant animals; clinical studies, that include non-pregnant women and provide data for assessing potential risks to pregnant women and fetuses 46.204(a) Risk to fetus is caused solely by interventions or procedures that hold prospect of direct benefit for the woman or the fetus or, 46.204(b) If no benefit, risk to the fetus is not greater than minimal and the research develops important biomedical knowledge not obtainable by any other means. 46.204(b) SPECIAL CONSIDERATIONS FOR PRISONERS The voluntary choice of the prisoners must not influenced by any potential advantages entailed to them due to the study, which outweighs the risks. For example, Parole decisions must not be affected for prisoners participating in the trial. The study is ethical, when the risk of participation is acceptable even to a non prisoner subject. Selections of subjects are carried out in a fair manner. When spoilt for choice, randomization techniques must be used. If necessary, adequate follow-up care must be provided to the volunteers. SPECIAL CONSIDERATIONS FOR DECISIONALLY IMPAIRED A combination of assent from the subject and permission from the concerned legal authorities constitute for the informed consent. The risk of participation would be agreeable to general volunteers too. Selection is fair and unbiased Adequate follow up is provided SPECIAL CONSIDERATIONS FOR SEX WORKERS Enrolling Sex workers in HIV vaccine trials that are ethical, valid and are not exploitative is a challenge that must be faced. Due to their nature of work, they require additional support. Sex workers are generally from the downtrodden community, they are illiterate and understanding the language in the informed consent is a major issue for them. Hence the informed consent must be in the local language and should be easily understood. The informed-consent must be prepared in such a way that it is in consultation with the community advisory and counsel board to ensure social sensitivity. Confidentiality is an important issue. These women may face physical abuse and abandonment from their clients, if they enter these trials. Supportive counseling should be provided before, during and after the test. Sex workers must not only be given male condoms but along with that they should be provided with female condoms. Proper guidance on safe sex must be dispensed. Clinical trial study team should increase awareness among the sex workers about AIDS. They should provide proper guidance to them, for prevention. Sex workers should be treated equally as general women would have been treated in a clinical trials. Study team should be sensitive towards them and not discriminate and look down upon them. CASE STUDY Health Minister, Urbain Olangnena Awono of the Cameroon government has decided that they may have to put a stop to the Tenofovir trials taking place in the port city of Douala due to various allegations by AIDS activists. The health minister had scheduled an audit for the same. The Tenofovir trial began in September 2004, Tenofovir is a established drug used for treatment of AIDS, manufactured by Gilead pharmaceuticals U.S. This trial was to determine whether Tenofovir can work as a prophylactic to prevent AIDS. The study recruited 400 sex workers free of infection. Half the women took a Tenofovir pill daily and the other half took a placebo. The study is conducted by Family Health and Insurance (FHI) with the support of U.S $ 6.5 million dollars from Bill and Melinda Gates Foundation. AIDS activists have demanded that this study be completely suspended on ethical grounds. They have said that the volunteers are vulnerable subjects and their rights have been exploited. Activists claim that the subjects have received inadequate counseling and healthcare. They have brought to notice that the sex workers are not fully informed about the risks involved in the trial. They also argue that the Study team has not promised to guarantee free healthcare if the workers become infected, which ideally every volunteer must receive. The FHI have counter attacked and cleared their stand by assuring that free medical checkups and tests have been carried out. Various tests like gynecological, medical care, HIV, pregnancy have been carried out for free. However various Activists have disregarded this claim and said that these are all false promises and haven’t been materialized. Another important issue that has been brought to notice was that, most of these sex workers were illiterate didn’t understand English and very little French, in spite of that the informed consent form were in English. However later it seen that the ICF shown to PlusNews was in French. The study team had provided 96 male condoms to sex workers. However imparting knowledge to prevent the infection of disease would be like a conflict of interest for the researchers. As the trial would be a success only if the women were exposed, become infected. The sex workers are misinformed and they feel that by taking this pill they are now vaccinated against the disease. In order to get their point across, so that the concerned authority would wake up to this injustice, AIDS activists in Paris staged a demonstration in front of the Cameroonian embassy in Paris. This demonstration got full coverage on the French T.V. This resulted in a public outcry against the trials. CRITIQUE The Tenofovir trial case study is an excellent example highlighting the profound impact media can have on the progress of the trial. The complete discontinuations of the trials prove that activists and non- governmental organizations with the help of the media can bring about change. These same activists are also involved in promoting research to combat the disease, but they can hinder the progress too. Hence researchers must be more aware about the ethical issues surrounding enrollment of sex workers. Engaging in discussion and consulting with the participant’s community before the trial begins can avoid such media spectacle. The case study rightly brings to one’s notice that lack of consultation with the support groups and community network was the biggest error on the part of the research team. Extensive discussion with community networks and a good flow of communication would bridge the gap and increase the trust of sex workers in the trials. The activists have rightly questioned why no subjects from general population have been enrolled to test safety of the drug. They have expressed concern and raised another important issue that the same trial would have provided women from Europe and U.S better benefits and adequate healthcare. The burning issue against this trial has been that since the primary outcome is HIV infection, researchers will provide inadequatecounseling to prevent infection. Since there exits a conflict of interest, sex workers will not be encouraged to have safe sex. Another important drawback of the trial has been its failure to provide sex workers with female condoms. They were provided with male condoms but negotiating for the same with their clients does not go down well with their trade. It is shocking that the sex workers were completely ignorant about the drug. They were misguided that the drug is a vaccine for AIDS, which made them more careless and prone to the disease. On the other hand, Tenofovir trials aimed at providing a prophylactic for AIDS, which would be a major breakthrough in combating this deadly disease and would definitely be of great benefit to the sex workers. Such uncontrolled and extreme protest has led to the complete discontinuation of the trial which in turn is bad news for the sex workers. The sponsor company had also promised to market this drug in Cameroon for much reduced prices. The validity of the media reports is doubtful as all the allegations made against the research team have been without any evidence. Activists instead of creating media backlash against the trial should have engaged in constructive dialogue with the research team stating their demands. CONCLUSION Clinical research has given millions of patients’ worldwide assurity that the medicine they purchase and consume, has been completely validated for its safety and efficacy. It ensures that these patients worldwide are getting the best medicine with utmost safety parameters. Investigators along with their research team bear the ultimate responsibility for their work with human subjects. They have the privilege of using human subject to advance scientific research, in turn society expects that investigators will show respect for their research subjects. Unfortunately as history has shown some scientists still continue to value their quest for knowledge and potential for personal fame and financial gain more highly then respect for basic human rights. Hence, various guidelines, regulations, codes and law have come into picture to protect the human subject. Special care and provisions must be made for subjects who are shunned from society. Sex workers live on the fringe of society and can rarely ask for their rights or support from public. In the interest of general health, to conduct trials for AIDS, this section of society must not be used as mere guinea pigs. Particular guidelines and ethical code of conduct for researchers must be drawn in order to protect these oppressed subjects. Providing them information on AIDS is not enough, they must be given free health care and female condoms. They need compassion and justice from us. REFERENCES Deanna Kerrigan et al, Environmental structural factors significantly associated with consistent condom use among female sex workers in the Dominican Republic, AIDS 2003 17:415-423 , Lippincott Williams and Wilkins. Arnaud L Fontanet et al, Protection against sexually transmitted diseases by granting sex workers in Thailand the choice of using the male or female condom: results from a randomized controlled trial, AIDS 1998, 12: 1851-1859, Lippincott Williams and Wilkins. Edward Mills et al, Media reporting of Tenofovir trials in Cambodia and Cameroon, 24 August 2005, BMC International Health and Human Rights. Edward J Mills and Sonal Singh, Health, human rights and the conduct of clinical research within oppressed populations, Globalization and health 2007, 3:10, BioMed Central Ltd. Peter H. Kilmarx et al, Protection of Human Subjects’ Rights HIV- preventive clinical trials in Africa and Asia: Experiences and Recommendations, AIDS 2001, 15 (suppl 5) : S73-S79, Lippincott Williams and Wilkins Geeta Yadav et al, Associations of sexual risk taking among Kenyan female sex workers after enrollment in an HIV – 1 prevention trial, J Acquir Immune Defic Syndr 2005; 38:329-334, Lippincott Williams and Wilkins Gielen AC, Fogarty L, OCampo P, Anderson J, Keller J, et al, Women living with HIV: Disclosure, violence, and social support, 2000, J Urban Health 77:480–491 R. Colombo, The Most Vulnerable Subjects Of Biomedical Research IX General Assembly PAV – publications. Urmila Thatte, Ethical issues in clinical Research chapter 4, of Basic principles of clinical research and methodology by S K Gupta Cynthia McGuire Dunn and Gary L. Chadwick, Protecting study volunteers in research, Third edition. Thomson Centerwatch. Ezekiel J. Emanuel, MD, PhD; David Wendler, PhD; Christine Grady, PhD, What Makes Clinical Research Ethical? , JAMA.2000;283:2701-2711. Cohen J. Cameroon Suspends AIDS Study. Science, Science Now 2005 Feb: 4. Singh JA, Mills EJ. The abandoned trials of pre-exposure prophylaxis for HIV: what went wrong? PLoS Med 2005;2: e234 Atatah C. Douala AIDS drug controversy: medical council says trials violated ethical norms. Post News Line 2005. www.postnewsline.com/2005/02/strongdouala_ai.html (accessed 15 Jan 2008). http://www.actupparis.org/article1734.html?var_recherche=tenofovir (accessed 15 Jan 2008) http://medicine.plosjournals.org/perlserv/?request=get-documentdoi=10.1371%2Fjournal.pmed.0020234ct=1SESSID=3b4fdb3c51bc2ee0983c4abb37ad4ffa (accessed 15 Jan 2008) KIPNIS K., Vulnerability in research subjects: a bioethical taxonomy, in NATIONAL BIOETHICS ADVISORY COMMISSION, Ethical and Policy Issues in Research Involving Human Participants, op. cit., vol. 2, pp. G1-G13, p. G5. http://www.academiavita.org/template.jsp?sez=Pubblicazionipag=testo/et_ricbiom/colombo/colombolang=english (accessed 15 Jan 2008) www.medscape.com/viewarticle/408956_3

Wednesday, September 4, 2019

Blackmur R.p., Form And Value :: essays research papers

Blackmur R.P., Form and Value in Modern Poetry, Doubleday, 1957. Justification This critique was first published as a journal article in The Southern Review, 1936 and later reprinted in the text entitled â€Å"Form and Value in Modern Poetry.† The author of the critique describes the meaning behind Yates’ poetry. He also describes Yates’ view of the world and explains how this influences the poetry and the response by many readers towards the work. Blackmur uses a comparison with other poets of the same era. Blackmur also describes in a way that is easily understood, the poetic devices employed by Yates in his works. Position of the writer The position of the writer, is that Yates is a great poet who combines technique with imagination. However, the content of his work and its symbolism is confronting to many readers and may not therefore appreciate the greatness of the poetry. The critics argument â€Å"The poet (and, as always the reader) has to combine, or fuse inextricably into something like an organic unity the constructed or derived symbolism of his special insight with the symbolism animating the language itself. It is, on the poet’s plane, the labor of bringing the representative forms of knowledge home to the experience which stirred them: the labor of keeping in mind what our knowledge is of: the labor of craft. With the poetry of Yates this labor is, as I say, doubly hard, because the forms of knowledge, being magical, do not fit naturally with the forms of knowledge that ordinarily preoccupy us.† What Blackmur is arguing, is that magic and the interpretation of this, is dependent on the reader’s knowledge of magic. He continues the argument, by implying that Yates believed that imagination was as valid a way of understanding the world as was logic. Blackmur also argues that because Yates has a view of life, that many readers do not share, the poetry is often interpreted as â€Å"sterile†. Exposition of the critics ideas and relevance Following the line of Blackmurs’ argument one can only appreciate the greatness of Yates’ poetry by understanding more about magic as a force in real life. However Blackmur claims that use of magic as a tool for poetry has two radical defects. The first defect is a lack of conventional authority outside the poem. The other defect is that Yates’ understanding of magic was not and could not be given in the words of the poem. Use of appropriate technical language Blackmur R.p., Form And Value :: essays research papers Blackmur R.P., Form and Value in Modern Poetry, Doubleday, 1957. Justification This critique was first published as a journal article in The Southern Review, 1936 and later reprinted in the text entitled â€Å"Form and Value in Modern Poetry.† The author of the critique describes the meaning behind Yates’ poetry. He also describes Yates’ view of the world and explains how this influences the poetry and the response by many readers towards the work. Blackmur uses a comparison with other poets of the same era. Blackmur also describes in a way that is easily understood, the poetic devices employed by Yates in his works. Position of the writer The position of the writer, is that Yates is a great poet who combines technique with imagination. However, the content of his work and its symbolism is confronting to many readers and may not therefore appreciate the greatness of the poetry. The critics argument â€Å"The poet (and, as always the reader) has to combine, or fuse inextricably into something like an organic unity the constructed or derived symbolism of his special insight with the symbolism animating the language itself. It is, on the poet’s plane, the labor of bringing the representative forms of knowledge home to the experience which stirred them: the labor of keeping in mind what our knowledge is of: the labor of craft. With the poetry of Yates this labor is, as I say, doubly hard, because the forms of knowledge, being magical, do not fit naturally with the forms of knowledge that ordinarily preoccupy us.† What Blackmur is arguing, is that magic and the interpretation of this, is dependent on the reader’s knowledge of magic. He continues the argument, by implying that Yates believed that imagination was as valid a way of understanding the world as was logic. Blackmur also argues that because Yates has a view of life, that many readers do not share, the poetry is often interpreted as â€Å"sterile†. Exposition of the critics ideas and relevance Following the line of Blackmurs’ argument one can only appreciate the greatness of Yates’ poetry by understanding more about magic as a force in real life. However Blackmur claims that use of magic as a tool for poetry has two radical defects. The first defect is a lack of conventional authority outside the poem. The other defect is that Yates’ understanding of magic was not and could not be given in the words of the poem. Use of appropriate technical language

Tuesday, September 3, 2019

The Civil Rights Act of 1964 Essay -- Civil Rights, Segregation, Equal

Before the Civil Rights Act of 1964, segregation in the United States was commonly practiced in many of the Southern and Border States. This segregation while supposed to be separate but equal, was hardly that. Blacks in the South were discriminated against repeatedly while laws did nothing to protect their individual rights. The Civil Rights Act of 1964 ridded the nation of this legal segregation and cleared a path towards equality and integration. The passage of this Act, while forever altering the relationship between blacks and whites, remains as one of history’s greatest political battles. Racial unrest by the summer of 1963 was at its height since the Civil War. President Kennedy picked up the situation at the close of the Eisenhower years at a time when tensions were rapidly increasing. By the summer of 1963, however, after a series of violent demonstrations in the South, particularly in Birmingham, Alabama, President Kennedy pushed for a very strong civil rights bill in Congress. The first of its kind since the Civil War, this bill drastically called for the end of all segregation in all public places. In the eyes of the civil rights movement leaders, this bill was long over due. Kennedy’s crusade began slowly to the dismay of many civil rights leaders in February of 1963. He began by sending the United States Congress a â€Å"Special Message on Civil Rights,† stating, Our Constitution is color blind, ...but the practices of the country do not always conform to the principles of the Constitution... Equality before the law has not always meant equal treatment and opportunity. And the harmful, wasteful and wrongful results of racial discrimination and segregation still appear in virtually every aspect of national life, in virtually every part of the nation (Loevy, 5). Kennedy received praise for these strong and moving words yet was criticized for his weak legislative proposals to remedy the situation. By May of 1963, his proposal would change greatly however, after two men, from opposite positions set the civil rights movement into intense motion. Martin Luther King despite advice to do otherwise began massive protests in the street of Birmingham. To combat these protests, Police Commissioner â€Å"Bull† Conner used any means, including dogs, fire hoses, and electric cattle prods on protestors. Making newspapers and televi... ...tates on a social level but politically too. This bill set the precedent for using a cloture to stop a filibuster in the Senate. Similar cloture votes in 1966 and 1968, with bills for equal voting rights and guaranteed equal housing respectively were used to stop Southern filibusters. The Civil Rights Act also proved that mass demonstration and peaceful protesting are heard in Washington D.C. Martin Luther King and the Leadership Conference started with nothing and achieved everything. From the segregated South those who fought for the Civil Rights Act of 1964 changed the course of American history and ridded the nation of inequality under the law. Works Cited Berman, Daniel M., A Bill Becomes a Law, The Macmillan company, New York: 1966. Levy, Peter B., The Civil RIghts Movement, Greenwood Press, Westport, Connecticut, 1998. Web. 24 June 2015. https://www.questia.com/read/10045885/the-civil-rights-movement Loeby, Robert D.,To End All Segregation, University Press of America, Maryland: 1990. Whalen, Charles and Barbara, The Longest Debate, Seven Locks Press, Washington D.C.:1985. Web. 3 July 2015. http://www.jstor.org/stable/27550291?seq=1#page_scan_tab_contents

Monday, September 2, 2019

Friendship in The Pact :: Personal Narrative Pact College Friends Essays

Friendship in The Pact Works Cited Missing Friendship can lift you up, strengthen and empower you, or break you down, weaken and defeat you† (32). In The Pact, George, Rameck, and Sam lifted each other through the hard times. They helped each other reach their dreams, even though they had their rough times. George, Rameck, and Sam all lived troubled lives while growing up. They all suffered with financial problems, and judicial problems. Their friendship helped them succeed and eventually gave them a more stable live style. Friendship is very powerful and can help you in so many ways. Many high school seniors are excited about going to college. Meeting new people, trying new things, and finding who they are, are all things they look forward to. But, not until a few days before the big move out, do they become nervous. To me, overcoming the transition to college was very difficult, and would have been more difficult if I did not have friends to encourage me. I was filled with excitement throughout the entire summer. I could not wait to get out of Scranton to expand my horizons. As the summer progressed, the excitement grew. When receiving the room assignments, I was shaking with nerves to see who I would be living with. I remember seeing their names and immediately forming a stereotype of them just by the looks of their name. A week before moving out, reality hit me like a gigantic rock. The feelings that were excitement were now anxiety. I was scared about leaving my safety zone. I knew many people in Scranton, and fit in well. I did not know anyone that was attending Penn State Harrisburg, I was alone for the first time in my life. I began to look at college as a fresh start of life. I had the opportunity to change anything I want about myself. However, the day before leaving, I wanted to change my mind, I no longer wanted to leave everything that I have known for my entire life. But, I refused to show my new feelings because I knew it was a common feeling among other college bound freshman. After some tears and deep breathes, I realized I always wanted to go away to school and if I backed out, I would regret my decision for the rest of my life.

Sunday, September 1, 2019

Chanting a Person’s Way to Salvation

Music lightens up the soul. Various kinds of sounds and rhythms are designed to touch and awaken the human heart. These are some of the reasons why music is considered universal, a medium that can be understood by anyone needless of any further explanation. In the world of various religions, music have been found as a useful instrument, either to encourage the praised God, or to encourage the followers. This is true not only in the present setup but even as far as the beginning of religion itself. Islam, Christianity and Shintoism are three varied religions originating in various parts of the world. How these three utilized music in their respective practices? Specifically, how musical chants are viewed by these especially during the period 200 CE to 1400CE? The debate whether the Prophet Muhammad meant that music is something considered   to be a vice still goes on. However, a religion not employing music in its rites or ceremonies seems to be an inexistent religion. The Quran does not say anything about music but if one gets near a Mosque, especially at noon and during Fridays, the chanting Imam’s voice can be heard as he leads the community prayer. Generally though, music is viewed as secular concern in Islamic religion, especially those that employ instrument. â€Å"The desert Arabs know no religious song and only sing of love and war in their old wild way† (S. M. Zwemer). However, chants existed and the Islamic chants in the early days were dedicated to the Prophet. In Mecca as well as in other â€Å"religious,† centres there is a sort of sacred-music of which Hurgronje gives several specimens. They are chants in honor of the prophet or prayers for him which are sung at the Moleeds or festivals in memory of Mohammed (S. M. Zwemer, 1900). Although music, as previously mentioned, is not promoted in Islam, the Arabians love for music were not hampered, which is totally different from the beliefs of the Mohammedans who consider music as one among the doubtful musements for true believers. The Catholic Church, referred as the â€Å"Western religion† in the early days have its purpose in using music. One very specific example is found in its ritual chant, which, eventually became the foundation of unaccompanied contrapuntal chorus based on the medieval key and melodic systems and also the foundation for the evolution of the present popular and dominant choir music which mixed solo and chorus music with free instrumental accompaniment, based on the modern transposing scales. As stated in the Catholic liturgy from the Missal, music are written to be sung. Unless they are put into tone, the words are useless.   Even in the early years, before the Carolingian Renaissance, Catholic chants already served as a supplemental and reinforcing element for the human emotions. In reading the words of the Catholic liturgy from the Missal we must remember that they were written to be sung, and in a certain limited degree acted, and that we cannot receive their real force except when musically rendered and in connection with the cere ­monies appropriated to them. For the Catholic liturgy is in conception and history a musical liturgy; word and tone are inseparably bound together. The imme ­diate action of music upon the emotion supplements and reinforces the action of the text and the dogmatic teaching upon the understanding, and the ceremony at the altar makes the impression still more direct by means of visible representation (Edward Dickinson, 1902). Chants are not as simple as the usual chorus sang these days. The early Catholic church have made chants very special and not easy to achieve. Why? With chants, it is not only employing voice and vocal quality. To serve the dogmatic nature of the religion, which was so strong at that time, chants must also be perfect to those who are strongly believing in the Church’s dogma. They must be done with interaction of both body and soul as the persons who do the chant put into action their praises to the Lord. All the faculties are therefore held in the grasp of this composite agency of language, music, and bodily motion; neither is at any point   independent of the others, for they are all alike constituent parts of the poetic whole, in which action becomes prayer and prayer becomes action (Edward Dickinson, 1902). Another known religion, which originated in Japan, employing chants in its practices is the Shintoism. In fact, this religion highly regards chant compared to other forms of music when it comes to religious and spiritual application. It is believed to be the God’s chant. According to Shinto Shaman Hideo Izumoto, â€Å"chants resonate the vibrations of the universe and power of creation.† In fact the 47 words of God in Shinto is chanted and it dates back as far as the religion existed and chants became an integral practice of Shintoism. These chants specifically refers to the forty-seven words of God, believed to have been given by angels centuries ago. Moreover, the same Shaman noted that singing God’s Chant daily is the simpliest way to prepare oneself for earth’s upcoming ascension. Even before the Japanese culture and religion was influenced by China and Korea in the sixth century, it has already a respectable culture of music. However, when it comes to Shintoism, the chanting was viewed as a borrowed practice from Buddhism. †¦Japan has received all teachings with open mind; and also that the instructions which came from outside have commingled with the native religion in entire harmony, as is seen by so many temples built in the name of truth with a mixed appellation of Buddhism and Shintoism†¦ (Walter R. Houghton, 1893). With all the three religions mentioned and how they look at music, there is only one underlying factor, the praising of their respective Gods. However, not all of the three mentioned look at music positively, as being the case of the Islamic practice.   However, for Christianity, specifically the western Roman Church, and the Japanese Shintoism, music is essential. With a single aspect of music which is chanting, it can be viewed that Shintoism has the strongest belief of the spiritual and physical effect of this kind of God-praising. It is a reasonable belief since chanting offers all of a person’s self, the concentration, the bodily movement, the language and of course the soul being offered to the God. This view is being shared by both Roman Catholic Christian and Shinto followers. Finally, music can be concluded as an integral part of one religion. Without music, religious rites and majority of its dogma would appear meaningless to its followers. With music, religious followers are exhilarated, resulting to jolly hearts ready to open and to accept what the dogma of their respective religions offer. Works Cited Dickinson, Edward. â€Å"Music in the History of the Western Church: With an Introduction on Religious Music among the Primitive and Ancient Peoples†. New York: Charles Scribner's Sons, 1902. 92. Houghton, Walter R. â€Å"Neely's History of the Parliament of Religions and Religious Congresses at the World's Columbian Exposition†. Chicago, IL: Frank Tennyson Neely, 1893. 158. Zwerner, S.M. â€Å"Arabia: The Cradle of Islam Studies in the Geography, People and Politics of the Peninsula, with an Account of Islam and Mission-Work†. Edinburgh: Oliphant Anderson and Ferrier, 1900. 278.